The aim of this paper is to establish a historical line from the first architectural application of structural elements made of industrial iron for roofs and multi-storey buildings to the first application of portal frame in a multi-storey building. With this in mind, the Crystal Palace built for the 1851 Great Exhibition held in London is revealed as the point of inflexion in the transition from metallic lattice typology, which is stabilized by perimeter masonry walls, to modern portal frame applied to the multi-storey building. Historical connections are detected in this transition giving value to some buildings which have remained on the side lines of the conventional architectural historiography. We can therefore expand on the traditional historical focus of the achievements of the Chicago School, highlighting and historically connecting prior events.